School of Industrial Sciences and Technology

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Author: search.filters.author.Magwa, M.LEnd date: 2666

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    The chemical composition and biological activities of essential oil from the fresh leaves of Schinus terebinthifolius from Zimbabwe
    (Academic Journals, 2009-12-15) Gweru, N; Gundidza, M; Magwa, M.L; Mmbengwa, M.V; Samie, A
    In the present study, the essential oil from the fresh leaves of Schinus terebinthifolius was extracted using the hydrodistillation method. The oil yield obtained was 0.65%. Gas chromatography and mass spectroscopy (GC-MS) analysis of the essential oil showed that the major constituents of the essential oil were sabinene, -pinene, -phellandrene, -pinene, terpinene-4-ol, trans--ocimene and myrcene. Using the hole-plate diffusion testing method, the essential oil exhibited potent antibacterial activity against Yersinia enterocolitica, Pseudomonas aeruginosa, Escherichia coli, Acinetobacter calcoaceticus, Bacillus subtilis, Klebsielia pneumoniae and Bacillus subtilis with at least 58% inhibition compared to the positive control. The mycelium growth inhibition method was used for anti-fungal testing. The essential oil exhibited activity against Aspergillus flavus with 58% inhibition, Candida albicans with 49.8% inhibition and Aspergillus niger with 48.7% inhibition. The -carotene, acetone and linoleic acid method was used to assess the antioxidant activity of the essential oil. The essential oil showed anti-oxidant activity of 13.1 mm mean zone of colour retention representing 72.7% activity compared to the positive control (ascorbic acid). This is the first study on S. terebinthifolius collected from sub-saharan Africa indicating the presence of trans--ocimene in the essential oil and its strong antibacterial activity against Y. enterocolitica and P. aeruginosa as well as moderate antifungal activities of the plant.
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    Aphrodisiac properties of some Zimbabwean medicinal plants formulations
    (African Journal of Biotechnology, 2009-11-16) Gundidza, G,M; Mmbengwa, V.M; Magwa, M.L; Ramalivhana, N.J; Mukwevho, N.T; Ndaradzi, A; Samie, A
    The aim of the present study was to determine the effects of formulations composed of Mondia whitei, Ekebergia capansis, aloe tincture (Aloe exelsa) and pumpkin seed (Cucurbita pepo) on sexual behaviour of inexperienced male rats. Male rats were treated orally with ethanol extracts of M. whitei and E. capensis, aloe tincture (from aloe juice) and pumpkin seed powder. The sexual behaviour of the rats treated with extracts was compared with those treated with 100 µg of testosterone as the positive control and those receiving normal rat feed as negative control. The receptivity of the females was rendered homogeneous with daily dose of estadiol benzoate. The sexual behaviour of the rats were observed over one ejaculatory phase for five consecutive days. The results showed a dose dependent increase in sexual arousability (decreased mounting latency), copulatory efficiency (decreased intercoupulatory interval) and improved sexual sensation (increased in neuromotor activity) for the rats treated with M. whitei and E. capensis, aloe and pumpkin seeds showing an increase in sexual performance in terms of intromissions and ejaculatory latency which also improved sexual sensation and coupulatory efficiency. The formulations of plants under investigation showed significant aphrodisiac properties.
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    Chemical composition of volatile constituents from the leaves of Aloe ferox
    (African Journal of Biotechnology, 2006-09-10) Magwa, M.L; Gundidza, M; Coopoosamy, R.M; Mayekiso, B
    Volatile compounds oils play a significant role in perfumery, cosmetic, medicinal and pharmaceutical industries. In our protracted research for new useful essential oils, a volatile oil from Aloe ferox was obtained by prolonged hydrodistillation. This volatile oil was subjected to GC/MS analysis to identify the major constituents of the oil. The major constituents identified were as follows: 3, 6 octatriene (23.86%), 3-cyclohexane-1-hetanol (7.31%), Bornylene (5.24%), 1, 3-cyclopentadiene (4.07) and 5-methyl3-heptanol (3.92%). A significant number of other volatiles were also identified but in minor concentrations.